Toxoplasma Gondii

For anyone familiar with the bleak early days of this blog back in November / December last year when the drama of this 2020 was still a thing of science fiction, I mentioned I was reading a book called Gut by Giulia Enders. Well it turns out I’m still reading it. This longevity isn’t because it’s difficult, quite the opposite in fact or boring, also quite the opposite. I just get distracted and either read other things or am too busy, but keep dipping into it when I fancy reading some more. This morning I read a little on Toxoplasma gondii. For anyone Scottish it is simply unimaginable not to be familiar with the film Trainspotting, and for those who are, they will be aware of this bacteria from the character Tommy catching it from his cat before dying from it and heroin. Naturally then this little mini-chapter grabbed my attention.

It turns out it’s actually an incredibly interesting bacteria which considering it’s size can have an enormous affect on it’s host. Cats, not all of course, carry this bacteria and it is spread to humans usually through their faeces in cat litter trays. It can find it’s way onto raw vegetables in your garden if a cat has either done it’s business or died within, as well as through animals such as pigs or chickens when we eat them. The chances of humans contracting toxoplasma are, in percentage terms, about as high as your age and about a third of the global population have them. We’re talking a reasonably high probability and billions of people. They don’t have an overly negative immediate affect on the human body, sometimes creating flu-like symptoms, so not too dissimilar to this virus for many people. Pregnant women though have to be very careful as it can damage the unborn baby and lead to miscarriages. What is fascinating about it though is the affect it has on our behaviour.

A study at Oxford University discovered rats, who would ordinarily and instinctively avoid cats urine, would when infected with toxoplasma not only be fearless of the cats urine but actively stay near it. This bacteria removed certain inhibitors in the rats brain, the bacteria which wanted to exist within the cats gut was offering up the rat, it’s host, as dinner and sacrifice. This tiny bacteria was influencing and arguably controlling the actions of a far larger creature. The rats were indifferent to human, dog and other varieties of urine, the rats and their cat loving bacteria interested in cats piss alone.

Like anything of this ilk proved on rats it wasn’t long before it was tested out on humans. She refers to a large scale experiement in which 3,890 soldiers from the Czech army were tested for toxoplasma and then over the next year the numbers of accidents they were involved in was recorded and analysed. It turned out those with the bacteria, and particularly those with rhesus negative blood type, were involved in the highest number of accidents. It turns out, and I’m going to crudely paraphrase this, that when infected the immune system activates an enzyme called IDO which breaks down a substance the invaders like to eat, forcing them to become dormant. Unfortunately this substance is also vital in the creation of serotonin, a lack of which is linked to depression and various anxiety disorders, as well as lethargy and general indifference. IDO is also highly activated during pregnancy, hence the link, and this and the immune systems response can sometimes treat the baby as a semi-alien which leads to miscarriages.

To take this further, the toxoplasma bacteria hide away in a few places but predominantly the amygdala section of the brain. This is also the area in which our fear receptors exist. This is also seemingly the part of the brain responsible for the decision making process, if you’re a parasite attempting to promote self-destructive tendencies, this is probably the best place to exist. Humans with toxoplasma were also found to have a different response to cats urine than those without, men especially seemed to prefer it with women less so. Interestingly the proportion of carriers among schizophrenics is about twice that among non-schizophrenics.

Science and medicine move slowly, unless you’re creating vaccines for pandemics of course, so it’ll still be a long time before these factors are tested for regularly and this understanding of behaviour and bacteria become common practice. It does though make you think about certain behaviours in people that just seem illogical and insane. Why someone could be so reckless is now slightly less inexplicable. Or even perhaps why you yourself have done so many stupid things over the years. I’m not suggesting we all go out and sniff cats urine to check our response of course, but this does open possibilities for how we view and understand behavioural patterns. This is just one parasite and if it’s possible for this one to create these suicidal and reckless tendencies, how do we know other bacteria don’t also affect our behaviours. There is so much we just don’t understand about our bodies yet we behave as if we know it all. The gut and the varieties of little enzymes and bacteria within can change everything about us yet we give it next to no attention. I am barely even a layman in regards to these things but it is exciting that we are starting to really see some movement and understanding of things within us that could potentially change our lives for the better. Who knows, if we can positively change our own behaviours with this, maybe science could save the whole world in a most highly unexpected of ways too. Either that or the cats may just take over the world after all.

Being Intolerant To Intolerances

I was hoping to think of something deep, intellectual, philosophical and meaningful to write about but I ate a pizza tonight and my stomach hurts. I can’t stop farting. It’s insane. Thankfully I enjoy and am a fan of a good fart so there is at least this pleasure to go with the pain in my stomach. The same thing happened last weekend after I had been eating pizza for a couple of day so I can only imagine it is the pizza. Saying that I had no problem the previous two weekends when I ate pizza the whole time. Maybe it has built up. It could be the onions and I will try one without them and without the sauce. If not I may have to face up to the horror that would be some kind of intolerance to the base. That would be an absolute nightmare. To make pizzas and not be able to eat them. It would nearly be as bad as having to tell people I’m gluten intolerant and watch as their faces change to disdain. A total nightmare all round.

I’m reading a book at the moment on the gut. I read this bit a few days ago and may have forgotten details but an intolerance is where the body can’t break down something in the food, it reaches the lymph glands or something like that and the body goes into overdrive trying to expel it because it thinks it is being attacked. Basically this is my body fighting back because it can’t deal with something I’ve ingested. It’s like when you get a fever this is the body increasing in temperature so as to kill any bacteria or virus within in, making itself inhospitable to survive in. Of course this feels rather unpleasant to us but it is worth remembering that this is actually a good sign. My body has decided to make itself inhospitable to something then. Fuck. I love food and I can’t think of anything worse than not being able to eat anything and everything I want. Maybe that’s the problem. A life without edible pleasures, a life less lived.

I don’t think it would be great to take what I said as fact in the last paragraph because I may have got it slightly confused with lactose intolerance which is about being unable to breakdown the lactose in dairy but the purge and inhospitable bodies isn’t far wrong. I’ve just drunk a cup of warm boiled water which seems to have helped somewhat. If in doubt just drink boiled water. I’m quite thirsty too and I’ve puffed up ever so slightly, not much but I’m a little pink. And just like that my dreams of a pizza empire have fallen flat. Could be for the best though because three days of eating pizzas each weekend is hardly going to do me any favours in the belly stakes, or heart either. Did you know when the body absorbs fats and oil they don’t go through the liver and kidneys like everything else to be filtered but instead bypass everything and go straight to the heart. That is a little worrying. Thirty four years old now. Already lost one friend my age to a heart attack. These things are serious. Maybe it’s time for the wholegrain pizza instead.

Salt Water Cleanse

You were warned earlier in the week that this day would come, and just like we’re seeing what’s happening in Australia when warnings are ignored, I’m about to write an intimate piece on my bowels. You may remember that I said my first attempt at making my own beer had failed and how it had forced me to become well acquainted with any nearby toilet I could find, well this went on until arguably Thursday. Yesterday my guts still seemed to be arguing with each other and because it had been a while today seemed like a good day for a clean.

There are various articles online describing more or less the same approach to a salt water cleanse. I learnt how to do it at a Rainbow Gathering in the Tasmanian bush about eight years ago and then discovered it again when doing a yoga course in India. I had a few years before this tried colonic hydrotherapy so lets say I’ve always been a fan. When I arrived in Australia I came from Burma and at some point in my month there I had eaten something which only upset my stomach for a couple of days but gave me the most horrendous smelly farts. A friend described it as if I was just oozing rot and decay with each puff. When I heard of the shitting / salt water cleanse workshop I was all in. Let’s just say I saw things that day that’ll never leave me, scars imprinted in the recesses of memory. A boy became a man.

It’s quite a simple procedure actually. It is important to do this on an empty stomach, so a light meal the night before and perform the cleanse prior to breakfast. Boil two litres of water, dissolve 2-3 teaspoons of mineral salt per litre – very important here not to use ordinary table salt as minerals in proper salt are important – and let it cool so it is warm but comfortable to drink. You drink half a litre and then do a series of five different yoga asanas dynamically, in repetitions of eight per asana, to help the water move through the body. These asanas are; Tadasana, Tiryaka Tadasana, Kati Chakrasana, Tiryaka Bhujangasana and Udarakarshanasana, I haven’t put them as links because I’m lazy and you’re capable of pressing copy and paste into an internet search engine. You then drink another half litre and repeat until you feel it impossible to hold in. Usually for me that is a litre and a half, but first couple of times was two litres. Even once you have released the trap door that first time I would still recommend you continuing to work through the asanas to help flush anything else out. Whatever stays inside of you will just be urinated out and I’m sure it’ll do the urethra no harm getting a little cleanse too.

I’m not suggesting for a second I’m a doctor and there are all sorts of articles online making all kinds of claims regarding health and mental improvement. I make no comment on them either way as I only know what I have experienced which is that when required it does seem to have completely flushed out whatever was inside my gut doing all the damage. In the early days too I did notice that it was a good indicator of foods which maybe didn’t suit me, such as dairy products which I immediately felt a little sick from and interestingly alcohol which I lost all desire for. I have ignored both those messages from my body clearly but it was interesting to see and maybe one day I’ll do something about them. The only thing I would say which could be a potential negative is that if it is flushing out the bad bacteria does that mean it is also flushing out the good bacteria, and that must be a genuine concern which I unfortunately don’t know the answer to. I have just started to read a book called Gut by Giulia Enders which seems really interesting, I am going to email her and see if she has any insight that she may like to share with me. It is also important to stress that for the rest of the day eating a very plain diet is important as the stomach has just gone through quite the workout. I have just enjoyed the most delicious soaked oats.